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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: Q01082




USC-OGP 2-DE database:  Q01082


Q01082


General information about the entry
View entry in simple text format
Entry nameSPTB2_HUMAN
Primary accession numberQ01082
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Spectrin beta chain, non-erythrocytic 1; AltName: Full=Beta-II spectrin; AltName: Full=Fodrin beta chain; AltName: Full=Spectrin, non-erythroid beta chain 1;.
Gene nameName=SPTBN1
Synonyms=SPTB2
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=4.73; Mw=33231

Cross-references
UniProtKB/Swiss-ProtQ01082; SPTB2_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameSPTB2_HUMAN
Primary accession numberQ01082
Secondary accession number(s) B2RP63 O60837 Q16057 Q53R99 Q59ER3 Q8IX99
Sequence was last modified on October 17, 2006 (version 2)
Annotations were last modified on March 15, 2017 (version 182)
Name and origin of the protein
DescriptionRecName: Full=Spectrin beta chain, non-erythrocytic 1; AltName: Full=Beta-II spectrin; AltName: Full=Fodrin beta chain; AltName: Full=Spectrin, non-erythroid beta chain 1;
Gene nameName=SPTBN1
Synonyms=SPTB2
Encoded onName=SPTBN1; Synonyms=SPTB2
Keywords3D-structure; Acetylation; Actin capping; Actin-binding; Alternative splicing; Calmodulin-binding; Cell membrane; Complete proteome; Cytoplasm; Cytoskeleton; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Repeat.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM96803; AAA60580.1; -; mRNA
EMBLAF327441; AAO15362.1; -; mRNA
EMBLAB209748; BAD92985.1; ALT_INIT; mRNA
EMBLAC093110; AAY24229.1; -; Genomic_DNA
EMBLAC092839; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH471053; EAX00147.1; -; Genomic_DNA
EMBLBC137282; AAI37283.1; -; mRNA
EMBLBC137283; AAI37284.1; -; mRNA
EMBLS65762; AAB28324.1; -; mRNA
EMBLAJ005694; CAA06678.1; -; mRNA
EMBLAJ238723; CAB91088.1; -; Genomic_DNA
CCDSCCDS33198.1; -. [Q01082-1]; .
CCDSCCDS33199.1; -. [Q01082-3]; .
PIRA44159; A44159; .
PIRA47213; A47213; .
RefSeqNP_003119.2; NM_003128.2. [Q01082-1]; .
RefSeqNP_842565.2; NM_178313.2. [Q01082-3]; .
RefSeqXP_005264574.1; XM_005264517.2. [Q01082-1]; .
RefSeqXP_006712150.1; XM_006712087.2. [Q01082-1]; .
RefSeqXP_016860268.1; XM_017004779.1. [Q01082-1]; .
RefSeqXP_016860269.1; XM_017004780.1. [Q01082-1]; .
RefSeqXP_016860270.1; XM_017004781.1. [Q01082-1]; .
UniGeneHs.503178; -; .
UniGeneHs.705692; -; .
PDB1AA2; X-ray; 2.00 A; A=173-280
PDB1BKR; X-ray; 1.10 A; A=172-280
PDB3EDV; X-ray; 1.95 A; A/B=1697-2015
PDBsum1AA2; -; .
PDBsum1BKR; -; .
PDBsum3EDV; -; .
ProteinModelPortalQ01082; -; .
SMRQ01082; -; .
BioGrid112589; 124; .
DIPDIP-33182N; -; .
IntActQ01082; 84; .
MINTMINT-1136298; -; .
STRING9606.ENSP00000349259; -; .
DrugBankDB01373; Calcium; .
iPTMnetQ01082; -; .
PhosphoSitePlusQ01082; -; .
SwissPalmQ01082; -; .
BioMutaSPTBN1; -; .
DMDM116242799; -; .
EPDQ01082; -; .
MaxQBQ01082; -; .
PaxDbQ01082; -; .
PeptideAtlasQ01082; -; .
PRIDEQ01082; -; .
EnsemblENST00000333896; ENSP00000334156; ENSG00000115306. [Q01082-3]; .
EnsemblENST00000356805; ENSP00000349259; ENSG00000115306. [Q01082-1]; .
GeneID6711; -; .
KEGGhsa:6711; -; .
UCSCuc002rxu.4; human. [Q01082-1]; .
CTD6711; -; .
DisGeNET6711; -; .
GeneCardsSPTBN1; -; .
H-InvDBHIX0002055; -; .
HGNCHGNC:11275; SPTBN1; .
HPAHPA012685; -; .
HPAHPA013149; -; .
MIM182790; gene; .
neXtProtNX_Q01082; -; .
OpenTargetsENSG00000115306; -; .
PharmGKBPA36104; -; .
eggNOGKOG0035; Eukaryota; .
eggNOGCOG5069; LUCA; .
GeneTreeENSGT00760000118813; -; .
HOVERGENHBG057912; -; .
InParanoidQ01082; -; .
KOK06115; -; .
PhylomeDBQ01082; -; .
TreeFamTF313446; -; .
ReactomeR-HSA-373753; Nephrin interactions; .
ReactomeR-HSA-375165; NCAM signaling for neurite out-growth; .
ReactomeR-HSA-445095; Interaction between L1 and Ankyrins; .
ReactomeR-HSA-5673001; RAF/MAP kinase cascade; .
ReactomeR-HSA-6807878; COPI-mediated anterograde transport; .
SignaLinkQ01082; -; .
SIGNORQ01082; -; .
ChiTaRSSPTBN1; human; .
EvolutionaryTraceQ01082; -; .
GeneWikiSPTBN1; -; .
GenomeRNAi6711; -; .
PROPR:Q01082; -; .
ProteomesUP000005640; Chromosome 2; .
BgeeENSG00000115306; -; .
CleanExHS_SPTBN1; -; .
ExpressionAtlasQ01082; baseline and differential; .
GenevisibleQ01082; HS; .
GOGO:0030673; C:axolemma; ISS:BHF-UCL; .
GOGO:0032437; C:cuticular plate; IEA:Ensembl; .
GOGO:0005737; C:cytoplasm; IDA:HGNC; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0031430; C:M band; IEA:UniProtKB-SubCell; .
GOGO:0005730; C:nucleolus; IDA:HGNC; .
GOGO:0014069; C:postsynaptic density; IEA:Ensembl; .
GOGO:0043234; C:protein complex; IEA:Ensembl; .
GOGO:0008091; C:spectrin; TAS:ProtInc; .
GOGO:0014731; C:spectrin-associated cytoskeleton; NAS:BHF-UCL; .
GOGO:0003779; F:actin binding; TAS:ProtInc; .
GOGO:0030506; F:ankyrin binding; IPI:BHF-UCL; .
GOGO:0045296; F:cadherin binding; IDA:BHF-UCL; .
GOGO:0051020; F:GTPase binding; IPI:UniProtKB; .
GOGO:0005543; F:phospholipid binding; IEA:InterPro; .
GOGO:0005088; F:Ras guanyl-nucleotide exchange factor activity; TAS:Reactome; .
GOGO:0003723; F:RNA binding; IDA:UniProtKB; .
GOGO:0005200; F:structural constituent of cytoskeleton; IMP:BHF-UCL; .
GOGO:0051693; P:actin filament capping; IEA:UniProtKB-KW; .
GOGO:0007411; P:axon guidance; TAS:Reactome; .
GOGO:0007182; P:common-partner SMAD protein phosphorylation; IEA:Ensembl; .
GOGO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome; .
GOGO:0043001; P:Golgi to plasma membrane protein transport; IMP:BHF-UCL; .
GOGO:0000165; P:MAPK cascade; TAS:Reactome; .
GOGO:0071709; P:membrane assembly; IMP:BHF-UCL; .
GOGO:0000281; P:mitotic cytokinesis; IMP:BHF-UCL; .
GOGO:0007009; P:plasma membrane organization; IMP:BHF-UCL; .
GOGO:1900042; P:positive regulation of interleukin-2 secretion; IMP:UniProtKB; .
GOGO:1903078; P:positive regulation of protein localization to plasma membrane; IMP:UniProtKB; .
GOGO:0072661; P:protein targeting to plasma membrane; IMP:BHF-UCL; .
GOGO:1903076; P:regulation of protein localization to plasma membrane; IGI:UniProtKB; .
GOGO:0007184; P:SMAD protein import into nucleus; IEA:Ensembl; .
CDDcd00014; CH; 2; .
Gene3D1.10.418.10; -; 2; .
Gene3D2.30.29.30; -; 1; .
InterProIPR001589; Actinin_actin-bd_CS; .
InterProIPR001715; CH-domain; .
InterProIPR011993; PH_dom-like; .
InterProIPR001605; PH_dom-spectrin-type; .
InterProIPR001849; PH_domain; .
InterProIPR018159; Spectrin/alpha-actinin; .
InterProIPR016343; Spectrin_bsu; .
InterProIPR002017; Spectrin_repeat; .
PfamPF00307; CH; 2; .
PfamPF00435; Spectrin; 17; .
PIRSFPIRSF002297; Spectrin_beta_subunit; 1; .
PRINTSPR00683; SPECTRINPH; .
SMARTSM00033; CH; 2; .
SMARTSM00233; PH; 1; .
SMARTSM00150; SPEC; 17; .
SUPFAMSSF47576; SSF47576; 1; .
SUPFAMSSF50729; SSF50729; 1; .
PROSITEPS00019; ACTININ_1; 1; .
PROSITEPS00020; ACTININ_2; 1; .
PROSITEPS50021; CH; 2; .
PROSITEPS50003; PH_DOMAIN; 1; .



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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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